Minipress (Prazosin) is an antihypertensive. Prazosin lowers, but does not cure, high blood pressure. It works by relaxing the blood vessels. Prazosin is sometimes used for prostate problems.
What should I tell my doctor before I take Minipress?
They need to know if you have any of the following conditions:
angina
kidney disease
an unusual or allergic reaction to prazosin, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I take Minipress?
Take prazosin capsules by mouth. Follow the directions on the prescription label. Swallow the capsules with a drink of water. Taking the capsules with food can help to reduce side effects. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your prescriber's advice.
Contact your pediatrician or health care professional regarding the use of Minipress in children. Special care may be needed.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What drug(s) may interact with prazosin?
Do not take prazosin if you are taking the following medications:
other alpha-blockers such as alfuzosin, doxazosin, phentolamine, phenoxybenzamine, tamsulosin, terazosin
Prazosin may also interact with the following medications:
medicines for colds and breathing difficulties
medicines for high blood pressure
monoamine oxidase inhibitors (Azilect®, Eldepryl®, Emsam®, Marplan®, Nardil®, Parnate®, Zelapar.)
sildenafil (doses of sildenafil higher than 25 mg should be taken at least 4 hours apart from taking prazosin)
tadalafil
vardenafil
water pills
Tell your doctor about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also tell your doctor if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your doctor before stopping or starting any of your medicines.
What side effects may I notice from taking prazosin?
Side effects that you should report to your doctor as soon as possible:
Rare or uncommon:
difficulty breathing, shortness of breath
prolonged painful erection of the penis (priapism)
More common:
blurred vision
fainting spells, lightheadedness
irregular heartbeat, palpitations or chest pain
mental depression
swelling of the legs and ankles
vomiting
Side effects that usually do not require medical attention (report to your doctor if they continue or are bothersome):
constipation or diarrhea
drowsiness or dizziness
dry mouth
headache
nausea
sexual difficulties (impotence)
stomach pain
unusual weakness or tiredness
What should I watch for while taking prazosin?
Check your blood pressure regularly. Ask your doctor what your blood pressure should be and when you should contact him or her.
You may feel drowsy or dizzy. Do not drive, use machinery, or do anything that requires mental alertness until you know how prazosin affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly. Avoid alcoholic drinks; they can make you more drowsy, and can increase flushing and rapid heartbeats. Taking initial doses of prazosin at bedtime can lessen the effects of drowsiness and dizziness, but be careful if you have to get up during the night. Drowsiness and dizziness are more likely to occur after the first dose, after an increase in dose, or during hot weather or exercise. These effects can decrease once your body adjusts to Minipress.
Although extremely rare in men taking prazosin, contact you health care provider immediately if you experience prolonged and painful erection of the penis which is unrelated to sexual activity (priapism). If not brought to immediate medical attention, priapism can lead to permanent erectile dysfunction (impotence).
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water, will help.
Do not take nonprescription medicine for weight-loss without asking your doctor. Also, do not take cough and cold, hay fever or sinus medications without asking your doctor.
If you are going to have surgery, tell your doctor that you are taking prazosin.
Where can I keep prazosin?
Keep out of the reach of children in a container that small children cannot open. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.
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