Provera
Generic name: Medroxyprogesterone
Provera tablets helps to treat an irregular menstrual cycle, lack of menstrual periods, or abnormal uterine bleeding caused by a hormonal imbalance. Medroxyprogesterone acts like the natural hormone progesterone. Natural progesterone is essential to normal reproductive functioning of the womb and reproductive system.
What should I tell my health care provider before I take Provera?
They need to know if you have any of these conditions:
asthma
blood vessel disease, blood clotting disorder, or suffered a stroke
breast cancer
heart, kidney or liver disease
high blood lipids or cholesterol
mental depression
migraine
seizures (convulsions)
vaginal bleeding
an unusual or allergic reaction to medroxyprogesterone, other hormones, medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I take Provera?
Take medroxyprogesterone tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. Take your doses at regular intervals. Do not take your medicine more often than directed. Bleeding generally begins in 3 to 7 days after completing the drug treatment.
Contact your pediatrician or health care professional regarding the use of Provera in children. Special care may be needed.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What drug(s) may interact with medroxyprogesterone?
antibiotics or medicines for infections, especially rifampin, rifabutin, rifapentine, and griseofulvin
barbiturate medicines such as phenobarbital, may be used to induce sleep or to treat seizures
bosentan
bromocriptine
medications for treating seizures (convulsions) such as carbamazepine, phenytoin, or primidone
modafinil
St. John's wort
Tell your doctor about all other medicines you are taking, including non-prescription medications, nutritional supplements or herbal products. Also tell your doctor if you are a frequent user of drinks with caffeine or alcohol, if you smoke or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What side effects may I notice from taking medroxyprogesterone?
Side effects that you should report to your prescriber or health care professional as soon as possible:
breast tenderness or discharge
numbness or pain in the arm or leg
pain in the chest, groin or leg
severe headache
stomach pain
sudden shortness of breath
unusual weakness or tiredness
vision or speech problems
yellowing of skin or eyes
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
changes in sexual desire or ability
changes in vaginal bleeding
facial hair growth
fluid retention and swelling
headache
increased sweating or hot flashes
loss of appetite or increase in appetite
mood changes, anxiety, depression, frustration, anger, or emotional outbursts
skin rash
stomach discomfort
weight gain or weight loss
vaginal yeast infection (irritation and white discharge)
What should I watch for while taking medroxyprogesterone?
Visit your doctor for regular checks on your progress. You should have a complete check-up every 6 to 12 months. Stop taking medroxyprogesterone at once and contact your prescriber or health care professional if you think you are pregnant.
The effect of medroxyprogesterone on fertility can last for a long time. If you want to get pregnant when you have stopped taking this medicine it may be some time before you can conceive.
Progestins can cause swelling, tenderness, or bleeding of the gums; be careful when brushing and flossing teeth. See your dentist regularly for routine dental care
Where can I keep my medicine?
Keep out of the reach of children in a container that small children cannot open. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.
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