Zestril (Lisinopril Hctz) is an antihypertensive (blood pressure lowering agent) known as an ACE inhibitor. Lisinopril controls high blood pressure (hypertension) by relaxing blood vessels. High blood pressure levels can damage your kidneys, and may lead to a stroke or heart failure. Lisinopril also helps to treat patients with heart failure (heart does not pump strongly enough).
What should I tell my doctor before I take Zestril?
They need to know if you have any of these conditions:
autoimmune disease (such as lupus), or suppressed immune function
previous swelling of the tongue, face, or lips with difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat (angioedema)
bone marrow disease
heart or blood vessel disease
low blood pressure
kidney disease
if you are on a special diet, such as a low-salt diet
an unusual or allergic reaction to lisinopril, other ACE inhibitors, foods, dyes, or preservatives
pregnant or trying to get pregnant
breastfeeding
How should I take Zestril?
Take Zestril pills orally. Follow the instructions on the prescription . Swallow the tablets with a drink of water. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking lisinopril except on your doctor's advice.
Contact your pediatrician or health care professional regarding the use of Zestril in children. Special care may be needed.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. If you take only one dose a day and forget to take it that day, do not take a double dose the next day.
What drug(s) may interact with lisinopril?
antiinflammatory drugs (NSAIDs, such as ibuprofen)
gold compounds, often used for arthritis
hawthorn
heparin
lithium
medications for diabetes
medications for hypertension
monoamine oxidase inhibitors (Azilect®, Eldepryl®, Emsam®, Marplan®, Nardil®, Parnate®, Zelapar.)
potassium salts
diuretics
Tell your doctor about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your doctor if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What side effects may I notice from taking lisinopril?
Side effects that you should report to your doctor as soon as possible:
decreased amount of urine passed
difficulty breathing, or difficulty swallowing
dizziness, lightheadedness or fainting spells
fast or uneven heart beat, palpitations, or chest pain
fever or chills
numbness or tingling in your fingers or toes
skin rash, itching
swelling of your face, lips, or tongue
Side effects that usually do not require medical attention (report to your doctor if they continue or are bothersome):
change in taste
cough
headache
tiredness
What should I watch for while taking Zestril?
Visit your doctor for regular checks on your progress. Check your blood pressure regularly while you are taking lisinopril. Ask your doctor what your blood pressure should be and when you should contact him or her. Call your doctor if you notice an uneven or fast heart beat. Do not treat yourself for a fever or sore throat; check with your doctor as these may be the result of a lisinopril side effect.
Check with your doctor if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of body fluid can make it dangerous to take lisinopril.
You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how lisinopril affects you. To avoid dizzy or fainting spells, do not stand or sit up quickly, especially if you are an older person. Alcohol can make you more dizzy. Avoid alcoholic drinks.
If you are going to have surgery, tell your doctor that you are using lisinopril.
Avoid salt substitutes or other foods or substances high in potassium salts.
Do not treat yourself for coughs, colds, or pain while you are using lisinopril without asking your doctor for advice.
Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.
Where can I keep my medicine?
Keep out of the reach of children in a container that small children cannot open. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture, Keep container tightly closed. Do not freeze. Throw away any unused medicine after the expiration date.
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