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Zimulti (Rimonabant)


Generic Zimulti 20.00 mg
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  Zimulti Zimulti (Rimonabant) is anorectic anti-obesity drug and it's the first in a new class of therapeutic agents called Cannabinoid-1 Receptor Blockers (CB1). 
Rimonabant used in the treatment of obesity and helps to quit smoking improves blood makers improves high-density lipoprotein (HDL) cholesterol and triglyceride levels. Zimulti (Rimonabant) used complementary to diet and exercise to treat obese or overweight patients who suffer from Type 2 diabetes and abnormal levels of fat in the blood. Zimulti (Rimonabant) can also prevent the risk of cardiovascular disease.

Also Rimonabant marketed under brandnames Acomplia, SR141716, Bethin, Monaslim, Remonabent, Riobant, Slimona and Rimoslim. 

How does Zimulti work?
 

Rimonabant works by selectively blockading CB1 receptors ascertained in the brain and in peripheral organs important in glucose and lipide (fat) metabolism, including fatty tissue, the liver, gastrointestinal tract and muscle. Rimonabant turns off the same brain circuits that form hungry when they smoke marihuana. 

CB1 receptor blockade with Rimonabant works to decrease the overactivity of the endocannabinoid system (EC system). The EC system are recently characterized physiological system that includes receptors such as the CB1 receptor and it has been shown to work an important function in regulation body weight and in controlling energy balance, as well as glucose and lipid (fat) metabolic process. 

What are the side-effects of Zimulti? 

Side effects in the trial on Zimulti in obesity were vomiting and nausea, forcing about 19 percent of patients to leave the trial versus 13 percent of those who took placebo. 

What is the shelf life of the Rimonabant? 

The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
 
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